Vitality into old age
Longevity aims to promote health and vitality into old age so that every stage of life can be active and fulfilling.
Longevity through cell health
Who wouldn’t want to stay active into old age, enjoy life, go traveling and be there for family and friends?
SenoFree® is a patented combination of herbal active ingredients that:
SenoFree® increases the chances of staying healthy and enjoying a high quality of life in old age.
What are senescent cells?
Senescent cells are cells that have lost their ability to divide and proliferate but are still metabolically active and have a high metabolic load. They are in a state of “biological aging“ and can no longer be repaired or replaced in the normal way.
Properties of senescent cells
Send out pro-inflammatory signals
Accelerate the aging process of the tissue
Increase the risk of age-related diseases
Risks of senescent cells
As we age, the immune system becomes less efficient at recognizing and eliminating senescent cells. The accumulation of these cells can negatively affect the surrounding tissue and increase the risk of chronic diseases, including:
Why remove senescent cells?
The Max Planck Institute for Biology of Aging in Cologne counts cellular senescence as one of the 12 central characteristics of ageing. If senescent cells can be removed, health improves and lifespan is extended.
What are senolytics?
Senolytics are active substances that specifically recognize and kill senescent cells. They support the immune system in eliminating senescent cells, which contribute to aging and the development of age-related diseases, as they release inflammatory and harmful substances.
Advantages of Senolytics
Senolytics is an emerging field of research in geriatric medicine. By reducing or delaying age-related problems, Senolytics can make an important contribution to extending the healthy lifespan (health span).
Selective removal of senescent cells
Slowing down the breakdown of tissue
Promotion of tissue regeneration
Improving general health
An effective senolytic
SenoFree® is a proven effective senolytic that can eliminate senescent cells. This can slow down the aging process and prevent age-related diseases, including:
What does SenoFree® contain?
SenoFree® combines various senolytically active plant substances, including:
The power of these ingredients has been proven to be used in senolytic therapies to promote health in old age.
How SenoFree® works
As we age, our immune system becomes inefficient at recognizing and removing senescent cells, which increase and accumulate in the tissue. The senolytic SenoFree® can specifically eliminate these senescent cells.
Senorevertika: Promote cell regeneration
Senorevertics are active ingredients that can reverse the process of senescence and reactivate senescent cells. In this way, they support the recovery of these cells and/or promote the formation of new cells.
The sister active ingredient SenoXure® performs precisely this task.
Combined therapy
A combination therapy with both classes of active ingredients is particularly promising for a healthy, long life. SenoXure® optimally complements the effect of SenoFree®.
Studies on SenoFree®
The active ingredient SenoFree® was tested in various studies. Of all the substances tested, the combination of flavonols (e.g. from the Japanese string tree) and lignans (e.g. from oatmeal) was able to reduce the proportion of senescent cells the most and below the baseline value.
Human lung tissue fibroblasts
Figure 1: Proportion of senescent cells in human lung tissue fibroblasts.
Human aortic endothelial cells
Figure 2: Proportion of senescent cells in human aortic endothelial cells.
Human progenitor cells
Figure 3: Proportion of senescent cells in human precursor cells of adipose tissue (subcutaneous preadipocytes)
Human mesenchymal stem cells
Figure 4: Proportion of senescent cells in human mesenchymal stem cells.
